This is the time of the death of all orthodoxies.

Greg Crowhurst 10/03/2009

The wrong side is where those gather to whose advantage it is to resist revolution.”

Colin Morris (1968) Include Me Out p. 63

I open an email early yesterday morning and two things happened all at once. A little bird told me off for implying in my latest article – Sound Familiar – that ME is heterogeneous , at the same time my wife staggered into the room, all bent over, unable to stand unsupported, needing my assistance to help her to be sick .

Gosh.

Courage, says Jon Nicol, in his incredibly uplifting piece on the internet is: “to remember that the worse critics will tell you only what you want to hear. The best critics are the honest ones.” www.musesmuse.com/00000508.html

Yes, it takes courage to listen and learn. The more I listened to what they had to say, the more I am convinced that the brave severe ME sufferer that emailed me is absolutely right.

I have, in fact, been declaring that ME is heterogeneous since 2005 when I published an article : “Understanding Severe Myalgic Encephalomyelitis “ in the Nursing Standard. I could not have been more explicit : “The disease is heterogeneous (composed of different elements) and it is not clear whether ME/CFS refers to a single condition or several distinct diseases that are bracketed together because of the similarity of their clinical appearance.

Too right – I stand by that statement, for it is still the prevailing orthodoxy – as far as I can make it out. Take Natalie Boulton’s extraordinary introduction to ME in Invest in ME’s just published book “Lost Voices.” I know of no better overview of the current medical and political issues in ME.

The reader , almost effortlessly , is shown how ME has a “very clear and thoroughly documented clinical history”, how ME is “properly described as an encephalitis associated with up-regulation of pro-inflammatory immune responses with down regulation of suppressor cytokines (Hooper2006) “how ME can be caused by “different viruses, bacteria and chemical toxins” and how potential sub-groups of ME have now been discovered ; “ there were marked differences between subtypes.. some of the subtypes had very poor mental health, others had a large degree of bodily pain, others a very small one, others a very good physical function, others very poor. Some people had gastrointestinal problems, where others did not; they had more prominent neurological symptoms, sore throat, headache etc.(Kerr 2008)”

So okay – am I technically wrong to use the word “heterogeneous” ? Clearly not –

but I am not so sure about it anymore.

“This is the time of the death of all orthodoxies and the destruction of all temples” declared Morris (1968), as well as the “destruction of all neat pigeon holes, all tidy explanations and lucid blueprints.”

The burning issue is this : to what extent does our orthodoxy play right into the destructive hands of the psychiatric lobby ? Indeed to what extent has the doctrine of heterogeneity, that I quote so unthinkingly, and perhaps wrongly, in ME, been dictated to or imposed upon an increasingly baffled patient group by the psychiatric lobby ?

For example, despite a damning critique of the CDC and Oxford Criteria ( apparently : “The new, revised and influential 2005 CDC Empirical ME/CFS definition, which identifies an even broader range of patients, has criteria which can even include people physically capable of running a marathon ! Boulton 2008) earlier in Lost Voices, it is striking how Dr Kerr’s research definition of distinct subgroups is based upon those self same CDC criteria.

Yes, I know it is also about funding issues. But….

What is truth ? Descartes said all we can reply upon ultimately is our own experience. My experience is that my wife was diagnosed with severe ME by Dr Betty Dowsett, back in 1997, who told us that my wife was extremely ill and continues to be, because of an eneterovirus.

Indeed before it was called “ME”, the disease was called “a-typical or posterior polio” and the early pioneers were in doubt, just as Dr Spurr is today, that “Enteroviruses…are the cause of Myalgic Encephalomyelitis. (Boulton 2008) ” The eneterovirus genus includes Polio, Coxsackie A&B, Echoviruses and E71; you do mess about with it.

Sadly the role of enteroviruses in ME “has gone largely unrecognised for many years. (Boulton 2008) Well, it doesn’t take a genius to figure out why that might be, given the shenanigans of McEvedy and Beard , the subsequent involvement of the dreaded psychiatric lobby back in the 1970’s and the Thatcherite/ New Labour multi-billion dollar stitch up, now coming horribly apart.

What has struck us, often forcefully over the years, is how our different our experience of ME is to most sufferers that we read about or ever so rarely come into contact with and yet how similar it is to those most severely affected, whom we never actually meet but have formed some very intimate bonds with.

To us, it is the severely affected who are the true ME sufferers. Sadly these are precisely the ones who are most excluded from research – hang on, I mean these are the ones that nobody I know off is researching right now, these are the ones most excluded from local patient group involvement , from any kind of service or effective advocacy.

These are the ones who actually die when exposed to CBT and GET.

These are the ones whose only constant is ongoing, dreadful physical suffering without end.

That is our truth and my eyes have been opened .

Plucking up the courage to break the rules, to speak heresy, to face excommunication, I declare here and now my instinctive opposition to sub-grouping; where is it going to get us and at what point is it going to stop : at 10, 20 or 100 subgroups ???

The goal posts keep getting wider, and all the time the psychiatric lobby is hooting and hollering right outside our window !

Of course I know many people are suffering right now from bacterial infections , from organochlorines, from pesticides, from insecticides and other toxins, that can lead to terrible, to tragic multisystem , inflammatory diseases.

At the end of the day, though, who does it benefit, apart from the medical insurance industry, to lump all these diseases together and call them “ME” ?

ME, dare I say it, always was and it always will be caused by an enterovirus. End of story. Enteroviral ME is “perhaps the largest, most deadly and most difficult to treat subtype of physical illness covered by ME/CFS definitions” (Boulton 2008).

If we are going to get anywhere : shouldn’t the word “subtype” be removed urgently from that sentence above ?

If we are going to start making a difference and relieving suffering: shouldn’t ME be defined categorically, as it originally was, as an enteroviral disease ? To hell with all those notions of “chronic fatigue” that have so deliberately muddied the waters.

The best , if not the only hope for true ME sufferers surely, is to honour the work of Richardson , Parish , Dowsett, Ramsay and focus all our attention on continuing the journey that they began , so rudely interrupted these many years, as Dr Chia is now doing .

EvME.

Or are we only playing word games ?